Did you know that the gut makes 90% to 95% of serotonin in the body, and that people with Carcinoid Syndrome can have serotonin levels greater than 5 times the average? An overproduction of serotonin by neuroendocrine tumor (NET) cells can lead to one of the most common and life-disrupting symptoms of excess serotonin, Carcinoid Syndrome diarrhea. Over time, too much serotonin increases the amount of fluid in the gut. It also speeds up the function of the gut, which causes frequent, or unpredictable diarrhea.
You know how diarrhea can feel a bit...sudden, like when a volcano erupts? In a volcano, when too much molten rock turns into lava, it rises to the surface and erupts. In your body, excess serotonin can have the same effect. Controlling serotonin levels may be key to avoiding frequent diarrhea.
There are other factors that can lead to Carcinoid Syndrome diarrhea, although higher serotonin levels normally play a role. Talk with your healthcare provider about whether too much serotonin could be the cause of your Carcinoid Syndrome diarrhea.